D. stramonium generally flowers throughout the summer. The fragrant flowers are trumpet-shaped, white to creamy or violet, and 6 to 9 cm (21⁄2–31⁄2 in) long, and grow on short stems from the places where the branches fork. The calyx is long and tubular, swollen at the bottom, and sharply angled, surmounted by five sharp teeth. The corolla, which is folded and only partially open, is white, funnel-shaped, and has prominent ribs. The flowers open at night, emitting a pleasant fragrance, and are fed upon by nocturnal moths.
